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Anatomy · Skull

Oral cavity

Cavitas oris

The oral cavity is bounded anteriorly by the lips, laterally by the cheeks, superiorly by the palate, and inferiorly by the tongue and the muscles of the floor of the mouth. The teeth and jaws divide this space into two parts: the vestibule and the oral cavity proper, which communicate with each other through the interdental spaces.

Key landmarkThe teeth and jaws divide the oral cavity into the vestibule and the cavity proper.
Parts of the lipThree parts are distinguished: the cutaneous part, the transitional zone (devoid of a stratum corneum), and the mucous membrane.
Parotid glandIts duct opens on the buccal mucosa strictly at the level of the upper second molar.
Mandibular canalServes as a pathway for the inferior alveolar vessels and the nerve of the same name.
4 min readFor medical studentsUpdated 19.09.2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Boundaries and divisions of the oral cavity

Topographically, the oral cavity is bounded anteriorly by the lips, laterally by the cheeks, the roof is formed by the palate, and the muscular floor and tongue are located inferiorly. Posteriorly, this space is open and transitions into the pharynx via the isthmus of the fauces (isthmus faucium).

The jaws and the teeth erupting from them divide the oral cavity into two functional zones:

  1. Oral vestibule (vestibulum oris) — the anterolateral part. This is a slit-like, horseshoe-shaped space bounded externally by the lips and cheeks, and internally by the gums and dental arches.
  2. Oral cavity proper (cavitas oris propria) — the postero-internal part located behind the teeth.

Communication between the vestibule and the cavity proper occurs through natural clefts — the interdental spaces.

Oral vestibule: lips and cheeks

Lips (labia oris) are folds consisting primarily of striated muscle. They are covered by skin externally and mucous membrane internally. Three zones are distinguished in the structure of the lip: the cutaneous zone, the transitional zone (where the skin lacks a stratum corneum), and the mucosal zone.

The upper lip (labium superius) is separated from the cheek by the nasolabial sulcus, and in the midline on its cutaneous surface runs the philtrum (philtrum), ending in a tubercle. The lower lip (labium inferius) is bounded inferiorly by the horizontal mentolabial sulcus. At the corners of the mouth, the lips merge to form the commissures (commissurae labiorum). Upon transitioning to the gums, the mucosa forms folds — the frenula of the upper and lower lips (frenulum labii superioris et inferioris). Motor innervation is provided by the facial nerve, while sensation is supplied by branches of the infraorbital and mental nerves.

Cheeks (buccae) also have cutaneous and mucosal coverings. Within their thickness lies the buccinator muscle (m. buccinator), and between it and the masseter muscle lies the buccal fat pad (corpus adiposum buccae). The mucous membrane of the cheeks gradually transitions into the gums (gingivae).

Test your knowledge on this topicExercises from the Anatomy course question bank with instant answers and explanations.

Mucous membrane and glands

The mucous membrane of the oral cavity (tunica mucosa oris) forms various folds, frenula, and elevations. The submucosa of the lips is rich in small labial glands (glandulae labiales). The cheeks also contain their own glands: buccal glands (glandulae buccales), whose bodies lie between the bundles of the buccinator muscle, and molar glands (glandulae molares), located in the region of the last molar tooth.

Special attention should be paid to the ducts of the salivary glands:

  • The duct of the parotid salivary gland (ductus parotideus) pierces the cheek and opens at the level of the upper second molar.
  • On the floor of the oral cavity lies the sublingual caruncle (caruncula sublingualis), where the ducts of the submandibular and sublingual glands open.
  • Extending from the caruncle is the sublingual fold (plica sublingualis).

Openings and canals of bony structures

To ensure the blood supply and innervation of the oral cavity, a system of openings and canals exists within the jaws and palate:

  • From the nasal cavity, the nasopalatine nerve (n. nasopalatinus) emerges onto the hard palate, passing through the incisive canals/foramina (canales/foramina incisiva).
  • The greater descending palatine artery and greater palatine nerve pass through the greater palatine canal (canalis palatinus major). They emerge into the oral cavity through the greater palatine foramen (foramen palatinum majus).
  • Similarly, lesser palatine vessels and nerves emerge through the lesser palatine foramina (foramina palatina minora).
  • The mandibular canal (canalis mandibulae) runs within the thickness of the mandible, into which the inferior alveolar vessels and nerve enter through the mandibular foramen (foramen mandibulae).
  • On the facial surface of the mandible, the mental foramen (foramen mentale) opens, through which the mental artery, veins, and nerve emerge (a., vv., n. mentales).
  • On the inner aspect of the mandible, the mylohyoid groove (sulcus mylohyoideus) is visible, along which run the artery and nerve branch of the same name.
How to memorize

Motor innervation of the facial muscles of the lips and cheeks is easy to remember through a single nerve: here, everything is controlled by the facial nerve (n. facialis).

Class and exam questions

What separates the vestibule from the oral cavity proper?

The jaws with the dental arches serve as the natural boundary. Communication between the compartments occurs exclusively through the interdental spaces.

Where does the excretory duct of the parotid salivary gland open?

It opens in the oral vestibule on the buccal mucosa; the landmark is the level of the upper second molar.

What emerges from the greater palatine foramen?

The greater palatine vessels (artery and vein) and the nerve of the same name emerge through the greater palatine foramen.

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What else to study on this topic

  • Blood supply and innervation of the lips and cheeks
  • Anatomy of the hard and soft palate
  • Topography of the buccal fat pad
  • Structural features of the mucosa of the floor of the oral cavity
  • Canals and foramina of the maxilla and mandible

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