Log in
Obstetrics and Gynecology · Obstetrics

Lactation

Lactatio

Lactation is the physiological process of breast milk production, accumulation, and excretion that begins within the first 24 hours postpartum. Successful lactogenesis provides the newborn with optimal nutrition and robust immune protection. Key roles in the establishment of lactation are played by hormonal adaptation, early breastfeeding initiation, and regular emptying of the mammary glands.

InitiationThe first breastfeeding attempt should occur within 30 minutes after birth.
Hormonal controlProlactin is responsible for milk secretion, and oxytocin for milk ejection through the ducts.
Immune protectionColostrum contains maternal immunoglobulins IgA, IgM, and IgG, which protect the infant.
Prevention of fissuresBefore mature milk comes in, nursing time should be limited to 5 minutes.
4 min readFor medical studentsUpdated Sep 20, 2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Physiological changes after childbirth

The postpartum period is accompanied by active recovery of the woman's body. The ligamentous apparatus of the uterus returns to normal mostly by the end of the 3rd week. The perineal muscles, if there was no trauma during childbirth, begin to restore their function in the very first days and regain normal tone by days 10–12. The anterior abdominal wall remains relaxed for a long time due to overdistension, and in multiparous women, diastasis recti in the umbilical region may persist for life. Against the background of these changes, the process of breast milk production is triggered.

Preparation and mechanisms of lactogenesis

During pregnancy, the mammary glands prepare for secretion under the influence of estrogens, progesterone, prolactin, and human chorionic gonadotropin (hCG). During this period, hyperplasia of the glandular lobules occurs, ducts and terminal alveoli develop, and blood flow increases significantly.

True lactogenesis (breast milk secretion) starts within the first 2–3 days postpartum. Milk excretion is ensured by two main mechanisms:

  1. Hormonal: oxytocin, released by the posterior pituitary gland, causes contraction of the myoepithelial cells surrounding the ducts. Prolactin is responsible for the actual production of secretion by alveolar cells.
  2. Reflexive: the excretion process is triggered and maintained by the stimulus of infant suckling.
Test your knowledge on this topicTasks from the "Obstetrics and Gynecology" course bank — immediate answers and explanations.

Evolution of secretion: from colostrum to mature milk

In the first 2–3 days, the glands produce colostrum (colostrum) — a thick, yellowish fluid with an extremely high caloric value.

  • Cellular composition: leukocytes (lymphocytes and segmented neutrophils), milk fat globules, and specific colostrum bodies (large, irregular cells with a pale nucleus).
  • Nutritional value: contains a high amount of proteins, fats, essential fatty acids, phospholipids, cholesterol, vitamins, hormones, and minerals.
  • Immunity: lymphocytes and maternal immunoglobulins (IgA, IgM, IgG) play a huge role in the formation of the infant's passive immunity.

Later, breast milk begins to be produced—the optimal food for an infant in the first year of life. It is characterized by high digestibility in the gastrointestinal tract and provides reliable protection against respiratory and intestinal infections.

Features of breast milk composition:

  • Proteins: protein fractions are completely identical to the maternal blood serum fractions and do not depend on dietary proteins. In the first days of lactation, the concentration of protein and salts is significantly higher than in subsequent periods.
  • Carbohydrates: compared to colostrum, breast milk contains a large amount of lactose.

Feeding guidelines and breast care

The intensity of milk production directly depends on the quality of breast emptying. On days 2–3, the breasts become uniformly dense and remain painless.

  • Regimen: regular feeding on demand (the infant's desire) is necessary. The infant is applied to each breast alternately, or to both during one feeding if milk supply is insufficient.
  • Hygiene: the glands are washed with warm water and soap before and after each feeding. The direction of movement must be strict: from the nipple to the axilla.
  • Prevention of problems: to prevent nipple fissures, careful visual inspection is important, and suckling time before full milk ejection should not exceed 5 minutes. Starting from the 3rd day, it is necessary to wear a bra.
  • Expression: indicated only at the beginning of feeding in case of hypersecretion, if the baby cannot cope with the volume. Excess milk should be expressed into sterile freezing bags. In case of pronounced engorgement (often occurs on days 3–4), fluid intake is restricted and physiotherapy is prescribed.

Organization of postpartum management

Normally, a postpartum woman stays in the postpartum ward for 3 to 5 days. The most appropriate placement is in single rooms with a bathroom, where rooming-in for mother and child is organized.

Medical staff adheres to an active management strategy: early mobilization implies that women get up within a few hours after both physiological and operative deliveries.

To monitor the condition in the postpartum period, the following must be assessed:

  • General well-being and body temperature.
  • Hemodynamic parameters (pulse, blood pressure).
  • State of the mammary glands and the nature of lactation.
  • Uterine contraction (involution) and lochia.
  • Physiological excretions (urination and defecation).

Special attention is paid to infection prevention. This includes cyclical ward occupation, strict adherence to asepsis and antisepsis rules, thorough sanitary processing of premises, and the use of disposable instruments. Patients with any signs of infection are subject to immediate isolation in the septic/observation ward.

How to memorize

To memorize hormone functions: PROlactin PROduces (responsible for secretion by alveolar cells), OXYtocin Emptying/OXYdation (causes contraction of myoepithelial cells and milk ejection).

Class and exam questions

When should the baby be put to the breast for the first time?

Feeding initiation should occur within the first 30 minutes after birth. This critically important rule applies even when the child is delivered via cesarean section under epidural anesthesia.

How does colostrum differ from mature breast milk?

Colostrum is secreted in the first 2–3 days; it is thicker, contains more proteins, salts, immunoglobulins, and specific cells. Mature milk has a significantly higher concentration of carbohydrates (lactose).

Is it necessary to express milk after each feeding?

No, regular expression is not required. It is indicated only at the beginning of feeding in case of hypersecretion, if the infant cannot cope with the volume of milk.

Does the shape of the breasts recover after lactation ends?

During involution (cessation of lactation), regression of the mammary gland occurs, but complete restoration of its original shape and tone does not happen.

Something unclear? Ask the AIThe AI tutor has read the material on "Lactation" and will explain it in simple terms.

What else to study on this topic

  • Uterine involution and characteristics of lochia
  • Restoration of the musculo-ligamentous apparatus after childbirth
  • Infection prevention and operation of the observation ward
  • Principles of active postpartum management
  • Cellular composition and immunological value of colostrum

Master the entire topic in the "Obstetrics and Gynecology" course

This is a summary. The course covers everything tested in classes and exams.

  • Complete study guide on "Lactation" and 973 other pages of the subject
  • Assignments and quizzes after every topic — just like in a colloquium
  • AI tutor answers questions on the topic anytime
  • 21 video lessons on the subject

Other topics in the "Obstetrics" section

Entire "Obstetrics" section

Prepared by WhiteCoat Pro faculty in accordance with the medical school curriculum. For educational purposes only.