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Obstetrics and Gynecology · Obstetrics

Physiological postpartum period

*Puerperium*

The postpartum period is a critical stage that begins immediately after the completion of the third stage of labor. During this time, global restructuring of the body occurs: organs return to their pre-pregnancy state, and the endocrine system shifts to support lactation.

DurationNormally 6–8 weeks, with the early stage lasting the first 2 hours.
Decrease in BCCBlood circulation volume decreases by 13% due to pooling in the abdominal cavity.
OvulationResumes in ~50 days without lactation and in more than 100 days with breastfeeding.
Dominance shiftThe gestational dominance in the central nervous system is replaced by the awakening of the maternal instinct.
4 min readFor medical studentsUpdated Sep 20, 2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Essence of puerperium and anatomical changes

Normally, the total duration of the postpartum period ranges from 6 to 8 weeks. Obstetricians pay special attention to the early postpartum period—the first 2 hours after the delivery of the placenta, when the most acute adaptation processes take place.

The core of this entire stage lies in the global restructuring of the mother's body. The process of involution is launched—the regression of those colossal changes that formed during pregnancy and labor. Organs gradually return to their baseline state. All these processes are strictly regulated by the complex interaction of the central nervous system, the endocrine apparatus, and the reproductive organs themselves.

However, involution does not affect everything. The main exception is the mammary glands. Their function does not fade after childbirth; on the contrary, it sharply activates. The lactation process can successfully continue for a year or even longer.

In addition, it is important to understand that certain anatomical changes remain with a woman for the rest of her life. Such irreversible consequences include:

  • change in the initial size and shape of the mammary glands;
  • transformation of the external os of the cervix (it permanently acquires a characteristic slit-like shape);
  • appearance of pronounced rugosity of the vaginal walls.

Hormonal restructuring and lactation

The hormonal status of the postpartum woman undergoes perhaps the most significant and abrupt changes. Immediately after delivery, there is a rapid drop in placental hormone levels in the blood. This drop serves as a signal for the hypothalamo-pituitary system to restore its habitual functioning.

A special place in endocrine regulation belongs to the process of milk production. It is divided into two functional stages:

  1. To initiate lactation, a powerful hormonal stimulus is required. The start is provided by the combined action of estrogens, progesterone, and prolactin.
  2. Subsequently, the maintenance of milk secretion and release is controlled predominantly by two hormones—prolactin and oxytocin.

The restoration of reproductive function directly depends on breastfeeding. As soon as the woman stops feeding (or if a natural decrease in prolactin expression occurs), the cyclical activity of the hypothalamo-pituitary-ovarian system restarts in the body. Concurrently, the full function of the thyroid gland and adrenal glands is completely restored.

The timelines for the appearance of the first ovulatory cycles are:

  • about 50 days in non-nursing mothers;
  • more than 100 days in women maintaining lactation.
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Nervous and cardiovascular systems

Central nervous system After childbirth, a woman's psyche and nervous regulation change radically. The famous "gestational dominance," which determined the woman's condition during pregnancy, fades away. It is replaced by the awakening of the maternal instinct.

During this period, predominant excitation occurs in the cerebral cortex. A pronounced lability of the psyche—emotional vulnerability and mood swings—is extremely characteristic of postpartum women. Against the backdrop of this instability in the postpartum period, depressions requiring attention from physicians are possible.

Cardiovascular system The mother's hemodynamics also goes through serious adaptation. After delivery, three key indicators decrease by approximately 13%:

  • blood circulation volume (BCV);
  • circulating plasma volume;
  • circulating red blood cell volume.

An interesting clinical fact: the decrease in BCV in the early postpartum period exceeds the actual blood loss during labor by 2–2.5 times. The pathogenesis of this phenomenon lies not in external blood loss, but in internal redistribution—massive pooling of blood occurs in the vessels of the abdominal cavity.

How to memorize

To easily remember irreversible anatomical changes after childbirth, use the "MSV" rule: Mammary glands (change shape), Servix (slit-like os), Vagina (rugosity).

Class and exam questions

When does the early postpartum period begin and how long does it last?

It starts the exact second the third stage of labor ends (the placenta is delivered) and lasts for exactly 2 hours.

Why does blood circulation volume drop sharply after childbirth?

The decrease in BCV is associated not only with physiological blood loss. The main reason is large-scale blood pooling in the abdominal organs, which causes the drop in volume to exceed actual blood loss by 2–2.5 times.

Which organs do not undergo involution after childbirth?

The only exception to the regression process is the mammary glands. Their function, conversely, sharply activates to ensure lactation and can persist for a year or longer.

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What else to study on this topic

  • Mechanisms of blood pooling in the abdominal cavity after childbirth
  • The role of estrogens, progesterone, and prolactin in initiating lactation
  • The shift from gestational dominance to maternal instinct
  • Prevention and diagnosis of postpartum depressions against the background of psychic lability
  • Restoration of the function of the hypothalamo-pituitary-ovarian system

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