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Anatomy · Angiology

Subclavian vein

Vena subclavia

Subclavian vein (vena subclavia) is a large venous collector of the systemic circulation, serving as the direct continuation of the axillary vein. It collects venous blood from the tissues of the upper limb and receives vessels draining blood from the superficial and deep structures of the thoracic and abdominal walls.

Boundary of originOuter margin of the 1st rib
OriginContinuation of the axillary vein
Important tributaryCephalic vein (v. cephalica)
4 min readFor medical studentsUpdated 09/24/2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Formation and topography

Anatomically, the subclavian vein (v. subclavia) has no distinct proper origin from small capillaries, as it serves as the direct continuation of the axillary trunk.

The clear topographical boundary where the axillary vein changes its name to the subclavian vein is the outer margin of the first rib. Upon reaching this point, the venous trunk courses centrally to further participate in forming the superior vena cava system.

Deep companion veins

The system preceding the subclavian vein receives deep veins adjacent to the branches of the axillary artery. They form paired companion veins (vv. comitantes) that collect blood from the deep tissues of the shoulder girdle and thorax. These include:

  • Humeral circumflex veins (vv. circumflexae humeri).
  • Subscapular veins (vv. subscapulares).
  • Lateral thoracic vein (v. thoracica lateralis).
Test your knowledge on this topicExercises from the Anatomy course question bank with instant answers and explanations.

Superficial veins of the thoracic and abdominal walls

Blood from the skin and subcutaneous tissue of the trunk drains via an extensive network of superficial veins that ultimately head toward the axillary cavity and further into the subclavian vein.

A key role here is played by the thoracoepigastric veins (vv. thoracoepigastricae). They originate in the lateral regions of the thoracic and abdominal walls. Ascending along the lateral surface of the thorax, they reach the axillary cavity. In their lower sections, these vessels form important anastomoses with the superficial epigastric vein (v. epigastrica superficialis).

The lateral thoracic vein (v. thoracica lateralis) also collects blood from superficial structures, receiving:

  1. Veins of the areolar venous plexus (plexus venosus areolaris), a superficial vascular network located around the nipple of the mammary gland.
  2. Veins draining blood from the serratus anterior muscle. These vessels are characterized by extensive anastomoses with the upper 6–7 posterior intercostal veins. In some cases, they may drain not directly into the lateral thoracic vein, but into the thoracoepigastric vein.

Superficial trunks of the upper limb

Venous outflow from the upper limb, which subsequently enters the subclavian vein system, is provided by large superficial trunks. Examination of the medial surface of the arm with the skin and subcutaneous adipose tissue removed reveals the following main channels:

  • Cephalic vein (v. cephalica). It runs along the lateral surface of the arm, ascends into the groove between the deltoid (m. deltoideus) and pectoralis major (m. pectoralis major) muscles, and then heads toward the infraclavicular fossa (fossa infraclavicularis).
  • Basilic vein (v. basilica). This trunk is located and runs along the medial surface of the arm.
  • Median cubital vein (v. mediana cubiti). A short but hemodynamically important vessel connecting v. cephalica and v. basilica in the cubital fossa.
  • Median antebrachial vein (v. mediana antebrachii). It runs along the anterior surface of the forearm and empties into the veins of the cubital fossa.

The topography of these veins is closely related to fascial landmarks: the fascia of the deltoid muscle (fascia deltoidea), pectoral fascia (fascia pectoralis), as well as the brachial fascia (fascia brachii) and antebrachial fascia (fascia antebrachii).

Briefly: answers to topical questions

Which vein does the subclavian vein merge with, and what vessel is formed as a result?

The subclavian vein merges with the internal jugular vein (v. jugularis interna), forming the brachiocephalic vein (v. brachiocephalica).

Features of this junction:

  • Localization — the process occurs posterior to the sternoclavicular joint.
  • Anatomical formation — the junction site of these two large vessels is called the venous angle (Pirogov's angle).

Which anatomical structures are located anterior to the subclavian vein?

Anterior to the subclavian vein lies the sternoclavicular joint (articulatio sternoclavicularis): the subclavian vein reaches its posterior surface, meaning it lies posterior to it.

Sources also indicate that the subclavian vein runs in the interscalene gap (spatium ante scalenum) anterior to the attachment site of the anterior scalene muscle (m. scalenus anterior).

Does the subclavian vein have valves, and where are they located?

The subclavian vein has its own valvular apparatus, represented by a bicuspid valve.

Features of its location:

  • Localization — located directly at the site of vessel confluence.
  • Topography — situated in the region of the venous angle, where the subclavian vein merges with the internal jugular vein (v. jugularis interna) to form the brachiocephalic vein.

Into which vein does the cephalic vein (v. cephalica) directly empty after passing the infraclavicular fossa?

The cephalic vein (v. cephalica) empties directly into the axillary vein (v. axillaris).

Topography of the terminal section of this vessel:

  • Direction — the vein heads toward the infraclavicular fossa (fossa infraclavicularis).
  • Deep transition — dives deep below the level of the clavicle.
  • Fascial relationships — pierces the medial part of the clavipectoral fascia (fascia clavipectoralis), after which it finally empties into the axillary vein.
How to memorize

To remember the superficial veins of the arm: "Cephalica strives for the head (lateral, upward to the clavicle), while Basilica is basic (medial)"

Class and exam questions

Where does the axillary vein end and the subclavian vein begin?

The precise anatomical boundary where the axillary vein transitions into the subclavian vein is the outer margin of the 1st rib.

Where does venous outflow from the mammary gland occur?

Blood from the superficial areolar venous plexus drains into the lateral thoracic vein.

Which veins are connected by the median cubital vein?

The median cubital vein (v. mediana cubiti) is an anastomosis between the lateral (v. cephalica) and medial (v. basilica) superficial veins of the arm.

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What else to study on this topic

  • Topography of the axillary cavity and its neurovascular bundle.
  • Anastomoses between the superior and inferior vena cava systems (caval-caval anastomoses) via the superficial abdominal veins.
  • Structure and blood supply features of the serratus anterior muscle.
  • Fasciae of the upper limb: fascia brachii and fascia antebrachii, their role in venous outflow.

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