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Anatomy · Anatomical structures

Interscalene space

spatium interscalenum

The interscalene space (spatium interscalenum) is an anatomical space located between the anterior and middle scalene muscles. It is covered by the prevertebral fascia. The subclavian artery passes through this space, and the cervical and brachial nerve plexuses are formed within it.

CoverCovered by the 5th layer of the cervical fascia (prevertebral layer)
VesselsContains the second part of the subclavian artery
NervesSite of formation of the cervical and brachial plexuses
2 min readFor medical studentsUpdated 09/24/2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Where is the interscalene space located and how is it formed?

The space is located between the anterior and middle scalene muscles.

Boundaries:

  • Anteriorly: anterior scalene muscle (m. scalenus anterior).
  • Posteriorly: middle scalene muscle (m. scalenus medius).

Fascial cover: The space is covered by the prevertebral fascia (V fascia according to Shevkunenko's classification). This fascia forms sheaths for the scalene muscles, which originate from the transverse processes of the cervical vertebrae. Extensions of the prevertebral fascia pass onto the trunks of the nerve plexuses and the subclavian artery, forming sheaths for them.

What passes through the interscalene space?

The neurovascular structures located inside the space are:

  • Subclavian artery (a. subclavia) — enters the space at the level of the 1st rib. Its second topographical part is located inside the space. Passing here, the artery forms the groove for the subclavian artery (sulcus a. subclaviae) on the upper surface of the 1st rib.
  • Costocervical trunk (truncus costocervicalis) — a branch of the second part of the subclavian artery.
  • Cervical plexus (plexus cervicalis) — its structures are formed within the space.
  • Brachial plexus (plexus brachialis) — is also formed in this space.
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Topography and adjacent structures

The interscalene space is connected to other topographical formations of the neck:

  • Antescalene space (spatium antescalenum) — located anterior to the anterior scalene muscle.
  • First part of the subclavian artery — the segment of the vessel from its origin to the entrance into the interscalene space. At this stage, the thyrocervical trunk (truncus thyrocervicalis) branches off from the artery — a short vessel (1–1.5 cm) originating from the anterosuperior wall of the artery before it enters the space.
  • Third part of the subclavian artery — begins at the lateral border of the anterior scalene muscle and extends to the clavicle. The length of the second, third, and fourth parts of the artery is 5–7 cm on both the right and left sides.
  • Prevertebral cellular space — a closed space located posterior to the V fascia. It is filled with the longus capitis and longus colli muscles and is bounded laterally by the transverse processes of the cervical vertebrae.

Class and exam questions

Which fascia covers the interscalene space?

The space is covered by the prevertebral layer — the V fascia of the neck according to Shevkunenko's classification.

Which part of the subclavian artery is located in the interscalene space?

The second topographical part of the subclavian artery (a. subclavia) is located inside the space.

Which nerve plexuses are formed in this space?

The cervical (plexus cervicalis) and brachial (plexus brachialis) plexuses are formed within the interscalene space.

Where does the thyrocervical trunk branch off relative to the interscalene space?

The thyrocervical trunk (truncus thyrocervicalis) branches off from the subclavian artery before it enters the interscalene space, belonging to the first part of the artery.

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What else to study on this topic

  • Prevertebral fascia of the neck
  • Subclavian artery (a. subclavia)
  • Antescalene space (spatium antescalenum)
  • Brachial plexus (plexus brachialis)

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