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Topographic Anatomy · Upper Extremity

Axillary region

Regio axillaris

The axillary region is a strategically important topographic and anatomical zone connecting the thorax, neck, and upper limb. When the arm is abducted, it forms the axillary fossa, inside which lies an extensive fascial space containing major vessels, nerve plexuses, and lymph nodes.

Structure of Subcutaneous FatThe adipose tissue has a cellular structure due to fibrous septa.
Key LandmarkThe tendon of the latissimus dorsi muscle is the key to the posterior wall of the fossa.
Common PathologiesDue to the abundance of skin glands, furuncles, atheromas, and hidradenitis frequently occur.
Neurovascular Bundle ProjectionThe vascular projection line runs toward a point 1 cm medial to the midpoint of the clavicle.
5 min readFor medical studentsUpdated 09/24/2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Boundaries and External Landmarks

The axillary region itself (regio axillaris) is bounded by muscular contours that are clearly visible upon inspection. The boundaries of the region should not be confused with the walls of the axillary fossa.

  • Anterior boundary: lower margin of the pectoralis major muscle (m. pectoralis major).
  • Posterior boundary: lower margin of the latissimus dorsi muscle (m. latissimus dorsi).
  • Medial boundary: a conventional line on the chest wall connecting the margins of the specified muscles.
  • Lateral boundary: a similar line connecting the muscles on the medial surface of the arm.

Some landmarks are closely related to the scapular region. The superior angle of the scapula corresponds to the level of the 2nd rib, the spine of the scapula (spina scapulae) to the 3rd rib, and the inferior angle to the 8th rib. Palpatorily, the most reliable landmarks are the medial border, inferior angle, scapular spine, and acromion. The projection of the lateral border of the scapula is traced along a line from the lateral part of the acromion to the inferior angle.

Layer-by-layer Structure

  1. Skin. Thin within the region itself, but thick and fixed closer to the scapula. Contains hair and numerous glands (sweat, sebaceous, apocrine). Their blockage leads to the formation of retention cysts (atheromas).
  2. Subcutaneous adipose tissue (SAT). Weakly developed, single-layered. Pierced by connective tissue septa extending from the skin to the deep fascia. Contains cutaneous nerve branches and superficial lymph nodes.
  3. Superficial fascia. Poorly developed, represented by thin layers.
  4. Deep fascia (fascia axillaris). Thin in the center of the region, perforated by gaps for vessels. Thickens at the borders and transitions anteriorly into the pectoral fascia, posteriorly into the thoracolumbar fascia, medially into the deep thoracic fascia, and laterally into the arm fascia. The suspensory ligament of the axilla (lig. suspensorium axillae) pulls it upward, forming the vault of the fossa.
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Walls of the Axillary Fossa

The axillary fossa (fossa axillaris) has the shape of a four-sided pyramid, the base of which is formed by the axillary fascia, while the apex is directed toward the middle of the clavicle.

  • Anterior wall: formed by the pectoralis major muscle, as well as the clavipectoral fascia (f. clavipectoralis) with the pectoralis minor muscle.
  • Medial wall: serratus anterior muscle (m. serratus anterior) and its covering fascia. The lateral thoracic artery and the long thoracic nerve of Bell (n. thoracicus longus) run along it from top to bottom.
  • Lateral wall: coracobrachialis muscle (m. coracobrachialis) and the short head of the biceps brachii. The neurovascular bundle runs along the inner margin of the former—this site is used for digital compression of the axillary artery.
  • Posterior wall: formed by fascia and muscles—the subscapularis and latissimus dorsi.

Openings of the Posterior Wall of the Fossa

A gap is formed between the muscles on the posterior wall, which is divided by the tendon of the long head of the triceps into two important anatomical openings:

  1. Quadrangular space (foramen quadrilaterum). Located more laterally.

Boundaries: superiorly — subscapularis and teres minor muscles; inferiorly — teres major muscle; medially — long head of the triceps; laterally — surgical neck of the humerus. Contents: axillary nerve (n. axillaris) and posterior circumflex humeral artery.

  1. Triangular space (foramen trilaterum). Located more medially.

Boundaries: superiorly and inferiorly — the same; laterally — long head of the triceps. Contents: circumflex scapular artery (a. circumflexa scapulae), passing into the scapular region.

Interfascial spaces communications

The adipose tissue of the axillary fossa contains 5 groups of lymph nodes (apical, central, lateral, anterior, posterior) and has multiple pathways of communication through which purulent-inflammatory processes can spread:

  • Proximally along the course of the neurovascular bundle — into the fascial spaces of the neck and further into the anterior mediastinum.
  • Distally — into the fascial space of the arm.
  • Through the clavipectoral fascia (along a. thoracoacromialis) — into the subpectoral space.
  • Through the quadrangular space — into the subdeltoid space.
  • Through the triangular space — to the posterior surface of the scapular region.
  • Between the deep surface of the scapula and the chest wall — into the subscapular space.

Briefly: answers to topical questions

Which branches arise from the axillary artery by its segments?

The branches of the axillary artery arise within the three topographical triangles of the anterior wall of the axillary fossa.

  • In the clavipectoral triangle (first part) arise:
  • Superior thoracic artery (a. thoracica superior)
  • Thoracoacromial artery (a. thoracoacromialis)
  • In the pectoral triangle (second part) arises:
  • Lateral thoracic artery (a. thoracica lateralis)
  • In the subpectoral triangle (third part) arise:
  • Subscapular artery (a. subscapularis)
  • Anterior and posterior humeral circumflex arteries (aa. circumflexae humeri anterior et posterior)

What is the topography of the elements of the axillary neurovascular bundle?

The elements of the axillary neurovascular bundle are arranged in a specific order from anterior to posterior and mediolaterally (mnemonic "VAPlex").

  • Axillary vein (v. axillaris) — the most superficial structure, lies anteriorly and medially.
  • Axillary artery (a. axillaris) — located posteriorly and laterally to the vein.
  • Brachial plexus (plexus brachialis) — located laterally and deeper than the artery.

In the second part, the cords of the brachial plexus surround the artery on three sides:

  • Lateral cord (fasciculus lateralis) — laterally.
  • Medial cord (fasciculus medialis) — medially.
  • Posterior cord (fasciculus posterior) — posteriorly.
How to memorize

It is easy to distinguish the apertures of the posterior wall by their lateral position: the quadrangular space is bounded by the humerus, meaning it is strictly lateral. The triangular space is bounded only by muscles — it is located more medially.

Class and exam questions

In what position should the axillary lymph nodes be palpated?

Palpation is performed with the arm adducted so that the axillary fascia is relaxed. The exception is Sorgius' node, which is palpated when the patient's arm rests on the doctor's shoulder.

Where is the projection of the axillary neurovascular bundle?

The projection line is drawn from the junction of the anterior and middle thirds of the lateral boundary of the region (on the arm) to a point located 1 cm medial to the midpoint of the clavicle.

At what level is it optimal to ligate the axillary artery?

To develop reliable collateral circulation, the artery should be ligated proximal to the origin of the subscapular artery (a. subscapularis) and both humeral circumflex arteries.

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What else to study on this topic

  • Formation and Branches of the Brachial Plexus in the Axillary Cavity
  • Collateral Circulation of the Upper Extremity
  • Topography of the Subscapular and Subdeltoid Spaces
  • Proper Fascia and Osteofascial Compartments of the Deep Back Muscles
  • Lymphatic Drainage from the Breast via Apical Lymph Nodes

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