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Psychiatry · Chapter 18. Classification of Mental Disorders

ICD-10 in Psychiatry

The International Statistical Classification of Diseases and Related Health Problems Tenth Revision (ICD-10) is a unified diagnostic standard. In the Russian Federation, it serves as the mandatory basis for resolving all legal and social issues in psychiatric practice, despite the existence of various theoretical approaches.

A unified languageA unified system allows physicians to conduct large-scale international studies.
Legal statusRussian legislation requires strict adherence to ICD-10 when establishing a diagnosis.
NosologyIt is based on the unity of etiology, pathogenesis, and clinical presentation.
Specifics of the ICDFormal criteria often require compromise and ignore the views of individual countries.
5 min readFor medical studentsUpdated Sep 25, 2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Significance of global statistical classifications

The implementation of a unified diagnostic language plays a fundamental role in the development of modern medicine. Statistical classifications, such as ICD-10, provide specialists worldwide with the opportunity to organize large-scale collaborative studies. The accumulation of global data leads to a deep understanding of the nature of mental illnesses and helps establish new, more effective systems of specialized care.

The process of creating such standards is always associated with compromises. To achieve universality, developers are forced to establish rigid formal frameworks and criteria for each disorder. The flip side of this approach is that the theoretical views and established beliefs of psychiatric schools in individual countries may be disregarded. Due to its pronounced formality, statistical systems cannot be static—they objectively require regular revision, discussion within the professional community, and official recognition at the state level.

In practical activities, attending physicians often rely on different principles for assessing a patient's condition. However, it is important to remember the legal status of the document: current Russian legislation strictly stipulates that any social and legal matters must be addressed exclusively in strict accordance with ICD-10 criteria.

The nosological approach in psychiatry

In addition to statistical recording, the nosological principle remains fundamental to medicine (the term originates from the Greek word nosos — disease). This approach implies a strict classification of diseases based on the commonality of three main factors:

  1. Etiology (the cause of onset).
  2. Pathogenesis (mechanisms of development).
  3. Uniformity of the clinical presentation (which includes characteristic symptoms, types of progression, and possible outcomes).

Based on the nosological principle, all psychiatric disorders are classified according to a number of specific criteria. Depending on etiology, endogenous, exogenous (including somatogenic), and psychogenic pathologies are distinguished. Evaluation of brain structures allows disorders to be divided into organic and functional.

Typical dynamics are also taken into consideration: these may be full-fledged diseases or processes (with acute, protracted, or chronic courses), pathological developments, as well as defects as irreversible outcomes. Depending on the severity of clinical manifestations, conditions are differentiated into severe (psychoses) and milder (neuroses). The potential outcome of the disease ranges from complete recovery or the formation of remission to the development of a defect or patient death.

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Nosological characteristics of major disorders

The application of the nosological approach allows for a clear characterization of key mental illnesses by assessing their onset, course, changes in the brain, and symptomatology.

  • Neuroses typically manifest in connection with experienced emotional stress. The course of the illness is protracted but non-progredient (does not worsen over time). Structural changes in the brain are exclusively functional in nature. The clinical picture features productive symptoms at the neurotic level, while negative changes are entirely absent. The outcome of the disorder is either recovery or the formation of a neurotic personality development.
  • Psychopathies are characterized by the fact that the onset of the disorder cannot be determined, as it is present throughout the person's entire life. There is no classic course. Changes are functional. Against the background of productive neurotic disorders, specific negative symptoms manifest—personality disharmony. There is no distinct outcome as such.
  • Bipolar affective disorder (BAD) arises spontaneously, predominantly at a young age. The process is chronic, autochthonous, and occurs in phases with characteristic seasonal exacerbations. Brain changes are functional. The patient experiences productive symptoms in the form of mania or depression, without the formation of a negative defect. This disorder has no specific final outcome.
  • Schizophrenia also has a spontaneous onset in youth. The disease proceeds as a chronic, autochthonous, and progredient (steadily advancing) process. Amid functional changes in the nervous system, a severe psychosis unfolds, accompanied by schizis (including delusions of control, hebephrenia, catatonia). Deep negative symptoms develop: personality changes in the form of apathy, abulia, ambivalence, and gross thought disorders. The predictable outcome is schizophrenic dementia, which is typically characterized by emotional blunting and schizophasia.
  • Alcoholism in its onset is closely linked to the social environment. The course is chronic and progredient. Unlike the previous pathologies, gross organic changes in the brain are present here. Productive symptomatology includes a pathological craving for alcohol and exogenous-type reactions. The negative pole is represented by organic-type personality changes and moral-ethical degradation. The predictable outcome is toxic encephalopathy and severe, life-threatening damage to internal organs.

Briefly: answers to topical questions

What criteria are included in the concept of etiology within the nosological approach?

The concept of etiology within the nosological approach includes criteria that divide disorders into three main groups. The nosological principle (from the Greek nosos — disease) implies the categorization of illnesses based on the commonality of etiology, pathogenesis, and uniformity of the clinical picture. According to the etiological principle, the following disorder criteria are distinguished:

  • Endogenous
  • Exogenous (including somatogenic)
  • Psychogenic

What types of exogenous and endogenous pathologies exist in psychiatry?

In psychiatry, specific types of endogenous and exogenous pathologies are distinguished, differing in origin and clinical manifestations.

Endogenous functional psychoses include:

  • Schizophrenia — a chronic, progredient disease with a spontaneous onset.
  • BAD (bipolar affective disorder) — a chronic, phase-oriented disease with a spontaneous onset at a young age.

Exogenous and organic pathologies include:

  • Alcoholism — a disease involving organic changes in the brain and exogenous-type reactions.
  • Organic brain diseases — brain lesions caused by infections, intoxications, trauma, tumors, or vascular diseases.
How to memorize

To remember the three pillars of the nosological principle, use the acronym EPC: Etiology, Pathogenesis, Clinical picture.

Class and exam questions

Is it mandatory to use ICD-10 in Russia?

Yes, the legislation of the Russian Federation explicitly requires the use of ICD-10 for resolving absolutely all legal and social issues in psychiatry.

What is the difference between functional and organic disorders?

This criterion is based on the presence of physical abnormalities in the structure of the brain. In organic diseases (e.g., in alcoholism), brain structure is damaged, whereas in functional disorders (schizophrenia, neuroses), no such changes are detected.

Does manic-depressive psychosis have negative symptoms or outcomes?

No. According to nosological characteristics, BAD proceeds with functional changes and productive symptoms (mania and depression), but without the formation of negative symptoms and without a final defect (outcome).

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What else to study on this topic

  • Criteria for endogenous, exogenous, and psychogenic disorders.
  • Differential diagnosis of neuroses and psychopathies.
  • Features of the progredient course of schizophrenia.
  • Schizis and productive symptomatology (catatonia, hebephrenia).
  • Development of organic changes and toxic encephalopathy in alcoholism.

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