Log in
Pediatrics · Additional topics

Stomatitis in children

Stomatitis

Oral mucosa lesions in children occur in various pathologies, ranging from herpangina and aphthous stomatitis to manifestations of systemic diseases and anemias. Timely differential diagnosis helps distinguish them from dangerous infections and formulate an appropriate treatment plan.

HerpanginaCaused by Coxsackie viruses A, accompanied by papulovesicles on the soft palate.
Aphthous stomatitisManifests as small oval erosions with a yellowish coating and a hyperemic rim.
Angular stomatitis"Angular cheilitis" at the corners of the mouth occurs in iron deficiency anemia and sideropenic syndrome.
Behcet's syndromeA chronic disease with recurrent painful oral ulcers and multi-organ involvement.
2 min readFor medical studentsUpdated 10.10.2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesPending instructor review

Viral and aphthous mucosal lesions

Among common oral cavity lesions, herpangina is notable, triggered by Coxsackie group A viruses. The disease begins acutely with fever and sore throat. On the second day, single grayish elements (papules and vesicles) with a hyperemic rim appear on the soft palate, faucial pillars, uvula, and tongue, healing within a few days.

Another common variant is aphthous stomatitis of various etiologies. The local status is characterized by the formation of small oval erosions with elevated edges, surrounded by a narrow rim and covered with an opaque yellowish coating.

Systemic causes and associated changes

Inflammation of the oral mucosa can be a manifestation of severe systemic pathologies:

  • Behcet's syndrome: a multisystem disease presenting with painful recurrent oral ulcers resembling aphthous stomatitis, followed by involvement of the eyes, blood vessels, and skin.
  • Iron deficiency anemia: iron deficiency in the body leads to sideropenic syndrome, a key manifestation of which in the maxillofacial region is cracks at the corners of the mouth (angular stomatitis).
  • Hematological and infectious complications: severe neutropenia in aplastic anemias or measles complications can be accompanied by deep bacterial and fungal lesions of the oral mucosa.
Test your knowledge on this topicTasks from the "Pediatrics" course bank — immediate answers and explanations.

Principles of therapy and care

Treatment of oral mucosal lesions and associated conditions depends on the established diagnosis:

  • For viral and aphthous processes, thorough oral hygiene and a sparing diet (semi-liquid food without irritating properties) are essential.
  • Anesthetics are used for pain relief before meals.
  • Antibacterial therapy is prescribed strictly when a secondary bacterial infection occurs.
  • In iron deficiency anemia, correction of iron deficiency is performed, eliminating trophic disorders of the mucosa.
How to memorize

Burning oral stomatitis—Coxsackie sits in the warmth. Afts turn yellow all around, and angular cheilitis matures at the corners (with iron deficiency).

Class and exam questions

What rash elements are characteristic of herpangina?

On the second day of the disease, single grayish papulovesicular elements with a hyperemic rim appear on the soft palate, faucial pillars, tongue, and uvula.

How do aphthous stomatitis and foot-and-mouth disease differ in differential diagnosis?

Aphthous stomatitis is not accompanied by a pronounced general toxic syndrome or skin lesions in the distal parts of the hands and feet.

What does the appearance of angular cheilitis (angular stomatitis) in a child indicate?

Angular stomatitis is part of sideropenic syndrome and indicates tissue iron deficiency characteristic of iron deficiency anemia.

Something unclear? Ask the AIThe AI tutor has reviewed the material on "Stomatitis in children" and will explain it in simple terms.

What else to study on this topic

  • Clinical presentation and differential diagnosis of foot-and-mouth disease
  • Periods, symptoms, and anti-epidemic measures in measles
  • Stages of development and laboratory diagnosis of iron deficiency anemia in children
  • Hemorrhagic syndrome and infectious complication syndrome in aplastic anemias
  • Manifestations of Behcet's syndrome involving internal organs and the central nervous system

Master the entire topic in the Pediatrics course

This is a summary. The course covers everything tested in classes and exams.

  • Complete study guide on "Stomatitis in children" and 3,738 more pages of the subject
  • Assignments and quizzes after every topic — just like in a colloquium
  • AI tutor answers questions on the topic anytime
  • 71 video lessons on the subject

Prepared by WhiteCoat Pro faculty in accordance with the medical school curriculum. For educational purposes only.