Log in
Histology · Additional topics

Renal papillae histology

papilla renalis

The renal papilla represents the apex of the renal pyramid of the medulla, projecting into the lumen of a minor renal calyx. On a histological specimen, its surface is identified by its specific epithelial lining and the openings of the papillary ducts.

LocalizationApices of the medullary renal pyramids
EpitheliumThe surface of the papilla is lined by transitional epithelium
Outflow structureThis is where papillary ducts open into the calyces
Number of pyramidsThere are 8–12 pyramids and papillae formed in the kidney
2 min readFor medical studentsUpdated 10.10.2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesPending instructor review

Macroscopic and microscopic organization

The renal medulla is formed by renal pyramids (pyramides renales), with a total count ranging from 8 to 12. The free tapering apex of each such pyramid forms a renal papilla (papilla renalis).

These structures project directly into the renal calyx, where the excretion of definitive urine is completed. Straight tubules and collecting ducts pass through the thickness of the medulla and at the level of the papillae, merging into terminal papillary ducts.

Features of histological structure

The histological composition of the renal papillae and the pyramids forming them is closely related to the terminal parts of the urinary tract in the renal parenchyma:

  • Collecting ducts run perpendicular to the organ surface, descending from the medullary rays into the pyramids.
  • At the apices of the pyramids, they unite into large papillary ducts.
  • Papillary ducts open on the surface of the renal papilla directly into the lumen of the minor calyces.
  • The surface of the papilla itself is covered with a special lining epithelium.
Test your knowledge on the topicTasks from the Histology course bank — instant answers and explanations.

Epithelial lining of the papillae

Upon microscopic examination, the cellular composition is a key diagnostic element of the renal papilla zone. The surface of the papilla projecting into the renal calyx is lined with transitional epithelium. The same lining is characteristic of the adjacent wall of the calyx itself, which ensures tissue resistance to constant contact with urine and changes in the volume of the cavities.

How to memorize

The pyramid points downwards: the apex is the papilla, and the outer surface features transitional epithelium facing the calyx.

Class and exam questions

What epithelium lines the surface of the renal papilla?

The surface of the renal papilla is lined with transitional epithelium, which also covers the adjacent renal calyx.

Where do the ducts at the apex of the renal pyramid open?

Papillary ducts, formed by the fusion of collecting ducts, open on the surface of the renal papilla into the lumen of the minor calyces.

How many renal papillae are formed in a single kidney?

The renal medulla is formed by 8–12 renal pyramids, the apices of which form a corresponding number of renal papillae.

Something unclear? Ask the AIThe AI tutor has read the material on "Renal papillae histology" and will explain it in simple terms.

What else to study on this topic

  • Structure and topography of the renal cortex and medulla
  • Classification of nephrons by their localization (cortical, intermediate, juxtamedullary)
  • Morphofunctional organization of the loop of Henle
  • System of collecting ducts and papillary ducts
  • Features of the blood supply to the renal medulla

Master the entire topic in the "Histology" course

This is a summary. The course covers everything tested in classes and exams.

  • Complete study guide on "Renal papillae histology" and another 3,485 pages of the subject
  • Assignments and quizzes after every topic — just like in a colloquium
  • AI tutor answers questions on the topic anytime
  • 137 video lessons on the subject

Other topics in the "Additional Topics" section

Free video lessons: histologyShort lessons with study notes — no registration required.

Watch lessons

Prepared by WhiteCoat Pro faculty in accordance with the medical school curriculum. For educational purposes only.