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Pharmacology · Agents Regulating Immune Processes

Bone marrow preparations

Myelopidum

Bone marrow preparations are represented by Myelopid, an agent derived from a culture of mammalian bone marrow cells. They are used in the combination therapy of secondary immunodeficiencies and to stimulate the body's defense mechanisms.

Source of derivationBone marrow cell culture of pigs and calves
Active componentsA complex of 6 myelopeptides with different activities
Main actionStimulation of T- and B-immune systems
Main indicationSecondary humoral immunodeficiencies
2 min readFor medical studentsUpdated 09/24/2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Composition and myelopeptides

The active principle of such medicinal products is a complex consisting of six myelopeptides. Each of them possesses a unique biological role:

  • Myelopeptide-1: responsible for enhancing the functional activity of T-helper cells.
  • Myelopeptide-3: selectively stimulates the phagocytic link of immunity.

Together, these components trigger proliferation and increase the functional capabilities of both T- and B-cells.

Pharmacodynamics of the drug

The pharmacological effects of Myelopid are aimed at correcting the body's defense mechanisms:

  1. Restoration of baseline parameters of the T- and B-systems in various immunodeficiency states.
  2. Stimulation of antibody production, which actively strengthens the humoral link.
  3. General increase in the functional activity of immunocompetent cells.

This complex effect allows for effective support of the body under increased immune loads.

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Indications for use

The clinical use of bone marrow agents is justified in several key areas:

  • Combination treatment of secondary immunodeficiencies, especially those accompanied by pronounced damage to the humoral link.
  • Prevention of infectious complications after trauma, surgical interventions, and in the setting of prior osteomyelitis.
  • Therapeutic practice in chronic pyoderma and non-specific lung diseases.

Side effects

Like any pharmacological agents of biological origin, drugs of this group may cause adverse reactions:

  • Systemic manifestations: patients may note general weakness, mild dizziness, and nausea.
  • Local reactions: pain and local tissue hyperemia are possible at the injection site.
How to memorize

MYELOPID: Elements of immunity naturally treat the organism by boosting immune activity.

Class and exam questions

What are the sources of bone marrow preparations?

It is produced from a culture of bone marrow cells of mammals such as pigs and calves.

What is the function of myelopeptide-3 within the drug?

This peptide is responsible for stimulating the phagocytic link of the immune system.

In which pulmonary pathologies is Myelopid prescribed?

It is used in the combination therapy of non-specific pulmonary diseases.

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What else to study on this topic

  • The role of myelopeptide-1 in the regulation of T-helper cells
  • Features of the stimulation of the humoral link of immunity
  • Prevention of infectious complications after trauma and surgery
  • Local and systemic side effects of myelopeptides
  • Indications in chronic pyoderma

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