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Biology · Methods and Forms of Reproduction

Asexual reproduction

Reproductio asexualis

Asexual reproduction is a form of offspring production in which new individuals develop from somatic cells of a single parent without the formation of gametes. Due to cell division by mitosis, all offspring represent exact genetic copies of the maternal organism—clones.

GeneticsThe offspring is a genetic copy of the parent (clone).
MechanismThe formation of new cells is based on the process of mitosis.
DistributionFound in prokaryotes, fungi, plants, and certain animals.
RoleEnhances stabilizing selection under constant environmental conditions.
5 min readFor medical studentsUpdated 09/24/2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Key Characteristics

Reproduction in biology is defined as an essential property of living systems to produce their own kind. Globally, it is divided into two pathways: sexual and asexual.

The key feature of asexual reproduction is that only a single parent individual or even a single cell is required to propagate the species. This process occurs without the involvement of sex cells (gametes). New organisms form exclusively from the somatic parts of the parent. Since mitosis serves as the universal cellular mechanism for such division, the resulting offspring receive an identical set of genes, thus becoming a genetic clone. This strategy is widespread among prokaryotes, the kingdom Fungi, and plants.

Main methods of asexual reproduction

Depending on the structural organization of the organism, nature employs different mechanisms for cloning the maternal individual.

1. Fission The most frequent method for unicellular organisms. The maternal form splits into two or more daughter cells.

  • Simple binary fission: the classical pathway for prokaryotes.
  • Mitotic binary fission: found in protozoans and unicellular algae.
  • Multiple fission (schizogony): the nucleus divides repeatedly inside the cell, forming multiple nuclei. Then each nucleus becomes surrounded by a portion of cytoplasm, and the cell breaks apart into numerous independent organisms. A prime example is the malaria parasite.

2. Budding New organisms form as local outgrowths (buds) on the parent's body. Subsequently, they may either detach and begin an independent life (as in freshwater hydra or yeast) or remain attached to the maternal body, forming colonies (characteristic of coral polyps).

3. Fragmentation The maternal organism literally breaks apart into several fragments, each of which regenerates the missing parts and develops into a fully functional individual. This method is observed in scyphozoan polyps, sea stars, flatworms (planarians), and the alga Spirogyra.

4. Polyembryony A special variant in which an embryo at early stages of development, rather than the adult organism, breaks into parts. It occurs in mammals, such as armadillos; in humans, this is precisely how monozygotic (identical) twins arise.

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Vegetative propagation and sporogenesis

These two methods are most characteristic of the plant world and fungi.

Vegetative propagation A new organism regenerates from a part of the vegetative body. In plants, tubers, rhizomes, runners, bulbs, leaves, or layers can serve this purpose. The process may occur naturally in the wild or be applied artificially by humans for breeding and agriculture.

Sporogenesis In this case, reproduction occurs through specialized cells—spores. They can be dispersed by wind or water, giving rise to new individuals. Sporogenesis is found not only in plants (mosses, ferns, algae) but also in fungi (Penicillium, cap fungi) as well as certain protozoans (phylum Apicomplexa).

Cloning as an artificial method

Cloning is an artificial method of asexual reproduction that has been actively developing since the early 1960s. Its core remains unchanged: it is the mitosis of a somatic cell from the source organism to obtain an exact copy.

  • In plants: the method consists of culturing cells of meristematic tissue on special nutrient media. The main goal is to obtain new, pure varieties.
  • In animals: a textbook example is Dolly the sheep (1997). Her creation required two individuals of different breeds. A somatic mammary gland cell was taken from the first (the donor) to obtain a nucleus with DNA. An egg cell was taken from the second (the recipient), and its own nucleus was removed. After transplanting the donor nucleus into the enucleated egg cell, an organism developed that was genetically completely identical to the donor of the nucleus, but phenotypically (externally) differed from the recipient sheep that carried the fetus.

Today, active discussions and theoretical work are underway regarding the possibility of human cloning, which generates serious ethical debates.

Biological significance

The evolutionary significance of asexual reproduction lies in the rapid increase in the number of individuals with a strictly defined set of traits. This contributes to maintaining the ideal adaptation of organisms to constant environmental conditions. From an evolutionary standpoint, this mode of reproduction greatly enhances the role of stabilizing natural selection, weeding out any disadvantageous deviations.

Briefly: answers to topical questions

Which pathogenic protozoans, besides the malaria parasite, reproduce by schizogony?

In addition to the malaria parasite, the following pathogen from the phylum Apicomplexa reproduces by schizogony:

  • Toxoplasma (Toxoplasma gondii)—a representative of the order Coccidia.

In this parasite, schizogony occurs within the cytoplasm of macrophages, representing asexual multiple fission. This ensures an increase in the number of parasites. Upon macrophage lysis, toxoplasms are released, accumulate in body cells, destroy them, and infect neighboring cells.

What is the difference between mitotic binary fission and simple binary fission in prokaryotes?

The main differences between these types of division lie in the types of organisms and the mechanism of genetic material distribution.

SignSimple binary fissionMitotic binary fission
OrganismsProkaryotesProtozoans and unicellular algae
MechanismDNA replication occurs prior to division; the distribution of newly synthesized DNA strands to daughter cells is mediated by attachment to the cytoplasmic membrane rather than a mitotic spindleThe mechanism of cell division is mitosis
Cell divisionA transverse septum formsThe maternal organism divides into two daughter cells

Which phases of the cell cycle precede mitotic division of somatic cells?

Mitotic cell division is preceded by interphase—the period of preparation of the cell for division, accounting for about 90% of the cell cycle time.

Interphase includes the following periods:

  • Presynthetic period ($G_1$)—the chromosome consists of a single chromatid, genetic makeup is $2n2C$.
  • Synthetic period ($S$)—DNA replication and sister chromatid formation occur, genetic makeup reaches $2n4C$ by the end of the period.
  • Postsynthetic period ($G_2$)—final preparation for mitosis, genetic makeup remains $2n4C$.
How to memorize

To remember the main forms of asexual reproduction, use the mnemonic PDF-VS: Budding (Pochkovanie), Division (Delenie), Fragmentation (Fragmentatsiya), Vegetative (Vegetativnoe), Sporogenesis (Sporoobrazovanie) (plus polyembryony and cloning as special cases).

Class and exam questions

What is schizogony?

This is multiple fission in which the nucleus divides many times, forming multiple nuclei. Then they become surrounded by cytoplasm, and the parent cell breaks down into numerous daughter cells (an example is Plasmodium).

Can the birth of human twins be considered asexual reproduction?

The formation of monozygotic twins relates to polyembryony—a form of asexual reproduction where a single embryo breaks into parts, from which genetically identical individuals develop.

How does the nuclear donor differ from the recipient in cloning?

The donor provides a somatic cell with genetic material, while the recipient provides an enucleated egg cell. The resulting clone will be genetically identical specifically to the donor.

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What else to study on this topic

  • Cytological mechanisms of mitosis as the basis of asexual reproduction.
  • The life cycle of the malaria parasite and the role of schizogony.
  • Differences between simple and mitotic binary fission.
  • Practical application of meristem cultures in plant breeding.

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