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Obstetrics and Gynecology · Gynecology

Uterine corpus cancer

*Carcinoma corporis uteri*

Uterine body cancer is a malignant neoplasm that requires a multidisciplinary approach to diagnosis and treatment planning. In modern gynecology, early visualization of pathological processes and their differentiation from benign conditions, such as uterine fibroids, is of key importance.

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DiagnosticsMandatory histological examination of the uterine mucosal curettage.
VisualizationUse of ultrasound, CT, and MRI to assess the extent of the tumor process.
SurgeryRadical surgeries include hysterectomy or amputation of the uterus.
Risk groupPatients with metrorrhagia and contact bleeding.
2 min readFor medical studentsUpdated Sep 20, 2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Diagnostic algorithm

To establish an accurate diagnosis and rule out concomitant endometrial pathology in patients with abnormal uterine bleeding, fractional diagnostic curettage is performed. The obtained material is sent for mandatory histological examination. When it is impossible to differentiate uterine tumors from retroperitoneal or abdominal neoplasms, high-tech visualization methods are used: CT and MRI.

Surgical tactics

Surgical intervention remains the mainstay of treatment. Depending on the clinical picture and the extent of the process, the scope of surgery is chosen:

  • Hysterectomy (total hysterectomy).
  • Supravaginal amputation of the uterus (subtotal hysterectomy).

The choice of surgical access (abdominal, laparoscopic, or vaginal) is determined by the size of the uterus, the location of the nodes, and the surgeon's qualifications.

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Indications for radical treatment

Radical surgery is indicated in the following cases:

  1. Rapid tumor growth (more than 4 weeks per year).
  2. Impaired blood supply or necrosis of the nodes.
  3. Localization of the process in the cervix.
  4. Growth of neoplasms in postmenopause.
  5. Pronounced patient anemia due to menometrorrhagia.
How to memorize

To memorize the indications for radical surgery, use the rule «B-R-N-Sh-A» (Large size, Rapid growth, Necrosis, Cervical localization, Anemia).

Class and exam questions

Why is it important to perform a histological examination?

Histology is the "gold standard" for confirming the diagnosis and ruling out a malignant process in any abnormal uterine bleeding.

In which cases is laparoscopy preferred?

Laparoscopic access is used when minimally invasive intervention is necessary, provided the size and location of the nodes allow for safe surgery.

What to do when nodes are detected in postmenopause?

Any growth of myoma nodes in postmenopause is a direct indication for surgical treatment due to the high risk of malignant transformation.

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What else to study on this topic

  • Classification of submucosal nodes according to the FIGO system (Wamsteker/ESGE).
  • Features of preoperative preparation using GnRH agonists.
  • Technique of transcervical hysteroresection.
  • Risks of uterine scar rupture in subsequent pregnancy.
  • Methods for preventing adhesions after myomectomy.

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  • Complete study guide on «Uterine body cancer» and 973 more pages of the subject
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Other topics in the "Gynecology" section

Background and precancerous diseases of the cervixCervical cancerUterine fibroidsEndometrial hyperplasiaEndometrial polypsUterine sarcomaIntrauterine synechiaeHysterectomy complicationsHysteroresectoscopyEndocervix

Prepared by WhiteCoat Pro faculty in accordance with the medical school curriculum. For educational purposes only.