Clinical manifestations
In the acute period, female patients complain of pain, itching, and burning in the affected area, as well as dysuria and a feeling of heaviness in the lower abdomen. In severe cases, systemic reactions are possible: low-grade fever, headache, and lymphadenopathy. Involvement of the nervous system is characteristic: irritability, sleep disturbances, and decreased performance are noted. It is important to remember that after the acute period ends (in 8–10 days), symptoms may subside, which does not mean recovery.
Diagnostics and differentiation
The diagnosis is established based on complaints, medical history data, and physical examination results.
- Laboratory methods: include PCR, ELISA, and direct immunofluorescence assay of discharge from the urethra, vagina, and cervical canal.
- Differential diagnosis: ulcerations must be differentiated from syphilitic ones (the hard chancre is characterized by density and absence of pain).
- Limitations: serological antibody tests are not an independent diagnostic criterion, as they only confirm the fact of infection.
Treatment Management
The goal of therapy is to suppress pathogen activity and boost immunity.
- Basic therapy: administration of antiviral drugs (acyclovir, valacyclovir) for a course of 5–10 days.
- Immunomodulation: includes the use of interferon inducers and specific immunomodulators.
- Local treatment: antiseptic management to prevent secondary infection.
- Partners: examination is mandatory, treatment is carried out in the presence of clinical signs.
GONO: G — Purulent discharge, O — Acute period (8–10 days), N — Nervous disorders, O — Mandatory partner screening.
Class and exam questions
Why is serology not the main diagnostic method?
Determination of antibodies in the blood only confirms the fact of past contact with the virus, but does not allow assessing the activity of the process and the localization of the infection.
Do I need to treat my sexual partner if they have no complaints?
Sexual partners are subject to mandatory examination, but specific treatment is prescribed only in the presence of clinical signs of infection.
How long does the acute period of the disease last?
The acute period usually takes from 8 to 10 days, after which visible clinical manifestations may disappear.
What else to study on this topic
- Features of immunobiological resistance of the macroorganism in relapses.
- Mechanisms of action of endogenous interferon inducers.
- Comparative characteristics of specific and nonspecific immunotherapy.
- Management tactics for patients with atypical forms of infection.
- Prevention of secondary infection during local therapy.
Master the entire topic in the "Obstetrics and Gynecology" course
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- Complete study guide on "Gonorrhea in Women" and 973 more pages of the subject
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Other topics in the "Gynecology" section
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