Log in
Neurology

Chapter 18. Instrumental and Laboratory Diagnostic Methods

4 topics with concise reviews: definitions, key facts, and class questions.

This chapter is dedicated to the key tools that transform a clinical neurological examination from an art into an exact science. The section covers both the classical foundations—the assessment of physiological and pathological reflexes—and high-tech diagnostics. We will analyze electrophysiological methods (EEG, EMG, evoked potentials), neuroimaging principles (CT and MRI), and specific laboratory tests, including cerebrospinal fluid analysis.

In practical classes and exams, you will most frequently be asked about diagnostic selection algorithms. You will be expected to clearly understand how CT differs from MRI in the hyperacute period of a stroke, what an epilepsy pattern looks like on an EEG, and what CSF changes are characteristic of bacterial meningitis. Instructors also love to test your knowledge of reflex arcs when pathological signs are detected.

Do not try to memorize every possible normal and pathological variant. Your goal is to understand the physical principle of each method so that in the future you can accurately order the appropriate study for a specific clinical case.

Section Topics

Frequently asked questions for this section

What does needle EMG show in a healthy muscle at rest?

Normally, with complete muscle relaxation, bioelectrical activity is completely absent.

What is the main limitation of electrophysiological methods?

In most cases, they lack nosological specificity. That is, the studies indicate the level, nature (axon/myelin), and degree of the lesion, but do not provide a precise diagnosis.

Why is CT performed first when a stroke is suspected, even though it does not visualize fresh ischemia?

CT is performed rapidly (about a minute) and reliably detects intracerebral hemorrhage. This is critically important for the immediate selection of the correct treatment strategy and saving the patient's life.

What are the normal cytosis parameters in CSF?

Normally, the cell count in cerebrospinal fluid should not exceed 5 per 1 µL, predominantly consisting of lymphocytes.

Master the entire topic in the "Neurology" course

This is a summary. The course covers everything tested in classes and exams.

  • 907 pages of study guides on all topics
  • Assignments and quizzes after every topic — just like in a colloquium
  • AI tutor answers questions on the topic anytime
  • 32 video lessons for the subject
All sections of the "Neurology" subject