In this section, we examine the Togaviridae family. It includes two medically important genera: vector-borne alphaviruses, which cause fevers and encephalitides, and rubiviruses — the causative agents of rubella, which are pathogenic only to humans.
We will systematically study the general properties of togaviruses, the morphology of the rubella virus, and the pathogenesis of acquired infection. A separate and most important module is dedicated to congenital rubella syndrome — one of the leading causes of severe congenital malformations.
In classes and exams, instructors always emphasize the teratogenic effect of the virus. You will be required to clearly know the classical Gregg's triad (eye damage, heart defects, and deafness), understand the mechanisms of vertical transmission of infection, and be confident in serological diagnostics (as part of the TORCH panel), which is critically important in pregnancy management.