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United States · NBME and FSMB

USMLE Step 2 CK practice questions

Step 2 Clinical Knowledge tests the application of medical knowledge to patient care under supervision: diagnosis, the next best step in management, prevention and ethics across all core clerkships. It reports a three-digit score. Below: 767 original practice questions in its style, grouped by topic, each with the answer and an explanation.

Topics16
Questions767
Options per question5
Explanationsevery question
USMLE Step 2 CK: mixed quiz across all topicsPick an answer to see the correct option and the explanation at once. Your best score is saved in this browser.

Questions by topic

Cardiology50 questions with explanationsPulmonology & critical care50 questions with explanationsGastroenterology & hepatology47 questions with explanationsNephrology, fluids & electrolytes42 questions with explanationsEndocrinology & diabetes49 questions with explanationsHematology & oncology49 questions with explanationsInfectious diseases44 questions with explanationsRheumatology & musculoskeletal45 questions with explanationsNeurology50 questions with explanationsPsychiatry48 questions with explanationsPediatrics50 questions with explanationsObstetrics49 questions with explanationsGynecology & breast50 questions with explanationsGeneral surgery & trauma50 questions with explanationsEmergency medicine & toxicology44 questions with explanationsEthics, patient safety & biostatistics50 questions with explanations
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Frequently asked questions

What does USMLE Step 2 CK test?

Step 2 Clinical Knowledge tests the application of medical knowledge to patient care under supervision: diagnosis, the next best step in management, prevention and ethics across all core clerkships. It reports a three-digit score.

Are these official USMLE Step 2 CK questions?

No. Official exam items are confidential. These are original questions written in the style of USMLE Step 2 CK for its content outline and checked by an independent model that solves each one blind.

How many questions are free?

All 767 questions in this bank, with answers and explanations, are free and need no account.

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USMLE Step 2 CK is administered by NBME and FSMB. WhiteCoat Pro is not affiliated with or endorsed by them. All questions are original practice items written by the WhiteCoat Pro editorial team with AI assistance and checked by a second, independent AI model that solves every question blind; items with a disputed key are removed. They are not real exam questions. Educational use only, not medical advice.