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Diagnostic Radiology · Diagnostic Radiology of the Abdominal Organs

Pancreas transplantation

Transplantatio pancreatis

Pancreas transplantation is frequently performed as part of a combined surgical intervention together with kidney transplantation. Multislice computed tomography (MSCT) serves as the primary diagnostic imaging modality for postoperative organ assessment and for guiding fine-needle interventions.

Combined surgeryOften performed as a single en-bloc graft with kidney transplantation in diabetes mellitus.
Transplant pancreatitisThe main CT sign of this pathology is marked edema of the transplanted tissue.
Biopsy instrumentationA 17-G coaxial needle is used as a guide for the 18-G cutting needle.
Approach selectionThe needle trajectory strictly depends on the tumor location and the position of adjacent organs.
4 min readFor medical studentsUpdated Sep 25, 2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Pancreas transplant imaging

Young patients suffering from type 2 diabetes mellitus (diabetes type 2) frequently require a multidisciplinary approach to treatment. Multislice computed tomography (MSCT) allows for a detailed visualization of anatomical features following surgical intervention.

During surgery, the pancreas is often transplanted concurrently with a kidney. In this procedure, transplantation is performed as a single en-bloc graft that necessarily includes the duodenal C-sweep (duodenal C-sweep). Preservation of this anatomical complex is critically important for the proper functioning of the transplanted organ and to ensure physiological secretion flow.

When postoperative complications develop, MSCT plays a key role in their early detection. The most common pathology is transplant pancreatitis (pancreatitis). On computed tomography scans, this condition manifests as marked diffuse or focal edema of the transplanted pancreatic tissue. Timely diagnostic imaging of this edema allows for prompt therapy adjustment and ensures graft viability.

CT-guided biopsy: general principles

In addition to assessing graft status, computed tomography is indispensable when performing targeted biopsy of malignant pancreatic neoplasms. The method allows real-time guidance of the instrument while avoiding vital structures.

The standard kit for performing a CT-guided biopsy involves a two-needle system. Initially, a 17-G coaxial needle is inserted to act as a reliable guide. Subsequently, an 18-G cutting biopsy needle is advanced through it to the target lesion to obtain histological material. The choice of a specific trajectory (approach) is dictated by the location of the tumor node and the presence of anatomical barriers along the needle path.

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Access approaches for biopsy of the pancreatic head

Neoplasms localized in the head of the pancreas require a special approach due to their close proximity to the stomach, intestines, and major blood vessels. Depending on the patient's individual anatomy, two main types of approaches are used:

  1. Anterior approach: Used when there is a safe window between the anterior abdominal wall and the tumor. In this case, the coaxial needle is advanced strictly from the anterior direction, reaching the target through structures of the greater omentum (omentum).
  2. Transgastric approach: If the neoplasm in the pancreatic head is obscured by the stomach and cannot be bypassed, a direct route is used. The needle is passed straight through the lumen and walls of the stomach to reach the tumor node.

Approaches to the body and tail of the pancreas

When the pathological process is localized in the body or tail of the organ, the trajectory selection strategy changes, as obstacles such as the colon, spleen, and left kidney come to the foreground.

  • Lateral antecolic approach: Optimal for biopsy of tumors in the body of the pancreas. In this option, the needle is inserted laterally, passing anterior to the colonic loops, which avoids perforating the colon.
  • Antecolic approach prone: Used for large tumors of the pancreatic tail. During standard diagnostic scanning in the supine position (supine), the tumor is often completely shielded (obscured) by the left kidney, spleen, and colon. To create a safe corridor for the needle, the patient must be turned to the prone position (prone position). Changing the body position causes internal organs to shift under gravity, creating a safe diagnostic "window" for advancing the needle anterior to the colon.

Briefly: answers to topical questions

What vascular anastomoses are created during pancreas transplantation?

During pancreas transplantation (pancreas), the formation of vascular anastomoses depends on the chosen surgical approach.

  • Organ transplantation — transplantation of organ fragments with creation of a vascular anastomosis in the iliac fossa.
  • Cell transplantation — isolated islets of Langerhans or pancreatic fragments are injected into the liver via the portal vein (v. portae).

Class and exam questions

Why is the duodenal C-sweep transplanted?

The pancreas is transplanted en bloc with the duodenal C-sweep to preserve the anatomical integrity of the ductal system and ensure adequate drainage of pancreatic secretions.

Through which anatomical structure does the needle pass during the anterior approach to the pancreatic head?

During the anterior approach to masses in the pancreatic head, the needle trajectory passes through the greater omentum.

Why is it necessary to change the patient's position to prone for a tail biopsy?

In the supine position, tail tumors are shielded by the kidney, spleen, and colon. Turning the patient to the prone position opens a safe window for needle insertion anterior to the colon.

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What else to study on this topic

  • Technique of combined pancreas and kidney transplantation
  • Complications following pancreas transplantation: imaging findings
  • Indications and contraindications for the transgastric approach in biopsy
  • Specifics of using 17-G/18-G coaxial systems in interventional radiology
  • Differential CT diagnostics of tumors of the pancreatic head, body, and tail

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