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Diagnostic Radiology · Diagnostic Radiology of the Abdominal Organs

Biliary tract injuries

Biliary Leaks and Bile Duct Injuries

Biliary tract injuries and bile leaks are serious conditions that most commonly result from trauma or prior cholecystectomy. Accurate application of diagnostic imaging methods, ranging from ultrasound to specialized cholangiography, is critically important for precisely assessing defect anatomy and selecting treatment tactics.

Main causeTraumatic impact or consequences of gallbladder removal.
Gold standardCholangiography to assess anatomy proximal to the duct injury site.
MRCP limitationsWithout contrast, it cannot differentiate bile from other fluid collections.
ClassificationBiliary cystic disease is described using the Todani system.
4 min readFor medical studentsUpdated Sep 25, 2026
Material prepared by WhiteCoat Pro editorial team based on platform study guidesReviewed by medical editor: Aulov A. A., general practitioner · 09/24/2026

Diagnosis of bile leaks and duct injuries

Ultrasound (US) and computed tomography (CT) serve as foundational tools. They effectively identify any fluid collections across all subphrenic spaces, but cannot precisely determine the nature of this fluid.

Endoscopic retrograde cholangiopancreatography (ERCP / ERCP) is extremely useful in patients after cholecystectomy. During this period, the probability of detecting residual stones is high. ERCP allows not only visualizing the problem, but also immediately performing stone extraction or placing a temporary stent. The main limitation: the method is uninformative if the duct has been completely transected or ligated.

Functional imaging includes HIDA scan and intravenous CT cholangiography (CT-IVC). These modalities can directly demonstrate the fact of a bile leak. For example, on CT-IVC after gallbladder removal, contrast can be seen extending beyond the biliary tree (often at the level of the cystic duct stump) and spreading toward the drain tube.

Magnetic resonance cholangiopancreatography (MRCP / MRCP) in standard non-contrast mode shows fluid collections well, but does not allow distinguishing bile from other substances. For accurate source identification, the use of a hepatotropic contrast agent and evaluation of T1-weighted images are required.

Tactics in the early postoperative period

When a severe bile duct injury is suspected, high-quality cholangiography becomes the most crucial examination. Its purpose is a detailed assessment of the anatomy proximal to the injury site.

If ERCP fails due to complete duct ligation, critically important information is provided by MRCP or CT-IVC. If the patient is scheduled for surgical reconstruction, the surgeon may require preliminary percutaneous transhepatic cholangiography (PTC / PTC).

Test your knowledge on the topicTasks from the "Diagnostic Radiology" course bank — instant answers and explanations.

Biliary cystic disease

Biliary cystic disease (Biliary Cystic Disease) is a rare pathology described by the Todani classification (Todani classification). Five types are distinguished:

  • Type I (79%): Choledochal cyst (choledochal cyst).
  • Type II (3%): Extrahepatic duct diverticulum.
  • Type III (4%): Choledochocele (choledochocele).
  • Type IV (13%): Multiple intra- and extrahepatic cysts.
  • Type V (1%): Caroli disease (Caroli disease).

Anatomically, types I and IV are distinguished by the presence of a long common channel (common channel) with the pancreatic duct, which is clearly visible on high-resolution MRCP. In type IV, MRCP reveals pronounced dilatation of the common hepatic and central intrahepatic ducts without peripheral dilatation.

Type I in children often manifests with the triad: jaundice and a palpable mass in the right upper quadrant. Symptoms of the other types resemble cholelithiasis. The pathology is dangerous due to complications: a high rate of stone formation and a 20-fold increased risk of cholangiocarcinoma.

To confirm communication of cysts with the ducts, contrast methods are required (ERCP, CT-IVC, PTC, contrast-enhanced MRCP). Standard non-contrast MRCP does not reliably show this communication. Duodenal duplication cysts communicating with the distal bile duct are less common (well visualized on CT-IVC).

Tumor pathology: Cholangiocarcinoma

Cholangiocarcinoma (Cholangiocarcinoma) is a rare tumor originating from the epithelium of the bile ducts, prone to local infiltration.

According to localization, they are divided into:

  • ~60%: Perihilar region (Klatskin tumours / Klatskin tumours).
  • <30%: Distal common bile duct.
  • ~10%: Peripheral (arising inside the liver, mimicking a parenchymal mass).
  • <10%: Diffuse or multifocal involvement.

Pathomorphologically, the most common growth patterns are "infiltrating stenotic" (infiltrating stenotic, usually <1–2 cm in diameter) or "exophytic" (exophytic, usually <5 cm). "Intraluminal polypoid" (intraluminal polypoid) and "mucin-secreting" (mucin-secreting) types are extremely rare.

How to memorize

To memorize Todani cyst frequencies: Type I (choledochal cyst) is the absolute leader (79%), Type IV (multiple) is second (13%), and the others are extremely rare (1–4%).

Class and exam questions

Which method best demonstrates a bile leak after cholecystectomy?

Functional methods: HIDA scan and intravenous CT cholangiography (CT-IVC). They are capable of directly demonstrating contrast extravasation outside the biliary tree.

Why is standard MRCP insufficient when a bile leak is suspected?

Non-contrast MRCP shows only the presence of fluid collection, but cannot differentiate bile from blood or exudate. Accurate diagnosis requires hepatobiliary contrast and T1-weighted images.

What is a Klatskin tumor and how common is it?

This is cholangiocarcinoma localized in the perihilar region. It accounts for about 60% of all cases of bile duct tumor pathology.

What is the main danger of biliary cystic disease?

In addition to a high rate of stone formation, this pathology increases the risk of developing biliary tumors by 20 times, primarily cholangiocarcinoma.

Confused? Ask the AIThe AI tutor has reviewed the material on "Biliary tract injuries" and will explain it in simple terms.

What else to study on this topic

  • Technique and interpretation of intravenous CT cholangiography (CT-IVC)
  • The role of percutaneous transhepatic cholangiography (PTC) in preoperative planning
  • Differential diagnosis of Todani cyst types on MRCP
  • Imaging semiotics of the infiltrating stenotic type of cholangiocarcinoma
  • Imaging features of duodenal duplication cysts

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