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Anatomy

Muscles of the Upper Extremity: Classification, Functions, and Clinical Significance

WhiteCoat Pro Editorial BoardApril 11, 20265 min read
Contents · 9 sections
  1. General classification of upper extremity muscles
  2. Muscles of the pectoral girdle
  3. Rotator cuff
  4. Muscles of the arm
  5. Muscles of the forearm
  6. Muscles of the hand
  7. Clinical correlations
  8. Exam mnemonics
  9. Frequently asked questions

The muscles of the upper extremity are one of the most comprehensive and practically significant sections of anatomy. Surgeons, traumatologists, and neurologists deal with these structures on a daily basis. This article provides a complete group-by-group classification, innervation, functions, and clinical correlations, complete with tables and exam mnemonics.

General classification of upper extremity muscles

The muscles of the upper extremity are divided into two major groups:

  • Muscles of the upper limb girdle (pectoral girdle) — connect the scapula and clavicle to the humerus
  • Muscles of the free upper extremity — muscles of the arm, forearm, and hand

There are over 50 muscles in total in the upper extremity. Each group has anterior (flexors) and posterior (extensors) compartments, determined by their position relative to the axes of joint movement.

Muscles of the shoulder girdle

The muscles of the pectoral girdle include six muscles that provide movement at the shoulder joint:

MuscleOriginInsertionFunctionInnervation
DeltoidClavicle, acromion, spine of scapulaDeltoid tuberosity of humerusAbduction of arm (anterior part — flexion, posterior — extension)Axillary nerve (C5-C6)
SupraspinatusSupraspinous fossa of scapulaGreater tubercle of humerusInitiates abduction (first 15°)Suprascapular nerve (C5-C6)
InfraspinatusInfraspinous fossa of scapulaGreater tubercleExternal rotation of the armSuprascapular nerve (C5-C6)
Teres minorLateral border of scapulaGreater tubercleExternal rotationAxillary nerve (C5-C6)
Teres majorInferior angle of scapulaCrest of lesser tubercleAdduction, internal rotation, extensionSubscapular nerve (C5-C7)
SubscapularisSubscapular fossaLesser tubercleInternal rotationSubscapular nerve (C5-C7)

Rotator cuff

Four muscles form the rotator cuff — a crucial structure for shoulder joint stability:

SITS mnemonic:

  • Supraspinatus
  • Infraspinatus
  • Teres minor
  • Subscapularis

The tendons of these muscles surround the head of the humerus superiorly, posteriorly, and anteriorly, forming a "cuff." Rotator cuff tears are one of the most common causes of shoulder pain in patients over 40. The supraspinatus tendon is injured most frequently (it passes beneath the acromion, the impingement zone).

Muscles of the arm

Anterior compartment (flexors)

Innervated by the musculocutaneous nerve (n. musculocutaneus, C5-C7):

  • Biceps brachii (m. biceps brachii) — flexion at the elbow joint, supination of the forearm. The long head originates from the supraglenoid tubercle of the scapula, the short head from the coracoid process
  • Coracobrachialis (m. coracobrachialis) — flexion and adduction of the arm
  • Brachialis (m. brachialis) — main flexor of the forearm (stronger than the biceps!)

Posterior compartment (extensors)

Innervated by the radial nerve (n. radialis, C6-C8):

  • Triceps brachii (m. triceps brachii) — the sole extensor of the forearm. Three heads: long, lateral, medial
  • Anconeus muscle (m. anconeus) — assists extension, tenses the capsule of the elbow joint

Forearm muscles

The most complex group — 20 muscles in four layers. Key for the exam:

GroupMain musclesInnervationFunction
Anterior superficialPronator teres, flexor carpi radialis, palmaris longus, flexor carpi ulnaris, flexor digitorum superficialisMedian nerve (except flexor carpi ulnaris — ulnar nerve)Wrist and finger flexion, pronation
Anterior deepFlexor digitorum profundus, flexor pollicis longus, pronator quadratusMedian + ulnar nerveFlexion of distal phalanges, pronation
Posterior superficialExtensor carpi radialis longus and brevis, extensor digitorum, extensor digiti minimi, extensor carpi ulnarisRadial nerveWrist and finger extension
Posterior deepSupinator, abductor pollicis longus, extensor pollicis brevis and longusPosterior interosseous nerve (branch of radial)Supination, thumb movements

Hand muscles

Three groups of intrinsic hand muscles:

  • Thenar muscles (base of the thumb): abductor pollicis brevis, opponens pollicis, flexor pollicis brevis, adductor pollicis
  • Hypothenar muscles (base of the little finger): abductor digiti minimi, flexor digiti minimi brevis, opponens digiti minimi
  • Central group: lumbricals (4) — flexion at metacarpophalangeal joints; palmar (3) and dorsal (4) interosseosti — adduction and abduction of fingers

Mnemonic for interossei: "PAD-DAB" — Palmar ADduct, Dorsal ABduct.

Clinical correlations

Upper limb nerve injuries produce characteristic clinical presentations:

InjuryClinical PracticeCause
Erb-Duchenne palsy (C5-C6)"Waiter's tip hand" — arm hangs by the side, medially rotated, extended at the elbowBirth trauma, arm traction
Radial nerve injury"Wrist drop" — inability to extend the wrist and fingersHumeral shaft fracture
Median nerve injury"Hand of benediction" — inability to flex I-III fingers into a fistWound in the cubital fossa
Carpal tunnel syndromeParesthesia of I-III fingers, thenar atrophyCompression of the median nerve in the carpal tunnel
Ulnar nerve injury"Claw hand" — hyperextension at metacarpophalangeal joints of IV-V fingersMedial epicondyle fracture

Exam mnemonics

  • SITS — rotator cuff (Supraspinatus, Infraspinatus, Teres minor, Subscapularis)
  • PAD-DAB — function of interosseous muscles
  • "Median prepares — ulnar cleans up" — the median nerve supplies flexors (prepares), the ulnar nerve supplies adductors and fine motor skills (cleans up)
  • Radial = extensors — injury → wrist drop (cannot extend)

Frequently asked questions

Which muscle initiates arm abduction?

The supraspinatus muscle (m. supraspinatus) initiates abduction in the first 15°, after which the deltoid muscle takes over the primary action. This is why in a supraspinatus tear the patient cannot initiate abduction, but if helped to raise the arm to 15-20°, they can manage the rest.

What is the difference between "claw hand" and "hand of benediction"?

"Claw hand" (ulnar nerve injury) involves hyperextension at the metacarpophalangeal joints and flexion at the interphalangeal joints of the IV-V fingers. "Hand of benediction" (median nerve injury) is the inability to flex the I-III fingers when attempting to make a fist.

Which nerve is most commonly injured in a humerus fracture?

The radial nerve — it runs in the spiral groove of the humerus and is particularly vulnerable in fractures of the middle third of the shaft.

Interactive upper limb anatomy lessons with tests and fill-in-the-blanks are available on the subject page. To reinforce your knowledge, use anatomy tests with answers, and for working with the skull, check out the article on skull bones. Also, see cervical triangles for topographical anatomy.

This material is educational in nature and does not replace a doctor's consultation. Verify treatment regimens and dosages with current clinical guidelines.

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