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General surgery

Acute Abdomen: Differential Diagnosis and Management

WhiteCoat Pro Editorial BoardApril 11, 20263 min read
Table of contents · 7 sections
  1. Definition and classification of causes
  2. Key symptoms and diagnostics
  3. Differential diagnosis by pain localization
  4. Examination algorithm
  5. Management: when to operate?
  6. Errors that must not be made
  7. Frequently asked questions

Acute abdomen is a collective clinical term encompassing emergency abdominal diseases and injuries requiring urgent surgical care. Correct differential diagnosis of the "acute abdomen" is one of the core skills for a physician of any specialty, upon which the patient's life depends.

Definition and classification of causes

Causes of acute abdomen are divided into three groups:

GroupMechanismExamples
InflammatoryInfection, autoimmune inflammationAppendicitis, cholecystitis, pancreatitis, diverticulitis, peritonitis
PerforativeLoss of integrity of a hollow organGastric/duodenal ulcer perforation, bowel perforation
Obstructive and ischemicDisruption of passage or blood supplyIntestinal obstruction, incarcerated hernia, mesenteric thrombosis, volvulus

Separately, gynecological causes (ectopic pregnancy, ovarian apoplexy, cyst torsion) and urological causes (renal colic, testicular torsion) are distinguished.

Key symptoms and diagnostics

Classical triad of the acute abdomen:

  1. Abdominal pain — the main symptom. Character, localization, and radiation indicate the cause
  2. Muscle rigidity of the anterior abdominal wall (defence musculaire) — a sign of peritoneal irritation
  3. Disrupted peristalsis — enhanced (mechanical obstruction) or weakened/absent (paresis, peritonitis)

Crucial peritoneal signs:

  • Blumberg's sign — pain intensifies upon sudden withdrawal of the hand from the abdomen (peritoneal irritation)
  • Rovsing's sign — pain in the right iliac fossa upon pressure in the left (appendicitis)
  • Murphy's sign — inspiratory arrest during palpation at the gallbladder point (cholecystitis)
  • Mayo-Robson's sign — pain in the left costovertebral angle (pancreatitis)
  • Hochenegg's sign — gaping anus, balloon-like ampulla of the rectum (sigmoid volvulus)

Differential diagnosis by pain localization

LocalizationMost probable causes
Right upper quadrantAcute cholecystitis, hepatitis, subphrenic abscess
EpigastriumUlcer perforation, acute pancreatitis, myocardial infarction (abdominal form!)
Right iliac fossaAcute appendicitis, mesenteric lymphadenitis, Crohn's disease, right-sided renal colic
Left iliac fossaSigmoid diverticulitis, sigmoid volvulus, left-sided renal colic
Umbilical regionEarly appendicitis (visceral pain), small bowel obstruction, mesenteric ischemia
Diffuse painGeneralized peritonitis, intestinal obstruction (late stage), mesenteric thrombosis

Examination algorithm

  1. Inspection and palpation — visual signs (distension, asymmetry), guarding, peritoneal signs
  2. Laboratory tests — CBC (leukocytosis, left shift), amylase/lipase (pancreatitis), hCG in women of reproductive age
  3. Plain abdominal radiography — free gas under the diaphragm dome (perforation), air-fluid levels/Kloiber's cups (obstruction)
  4. Abdominal ultrasound — free fluid, gallstones, appendix >6 mm, aortic aneurysm
  5. Contrast-enhanced CT — gold standard for an unclear clinical picture
  6. Diagnostic laparoscopy — when doubts persist

Management: when to operate?

Absolute indications for emergency surgery:

  • Hollow organ perforation (free gas on X-ray)
  • Ongoing intra-abdominal bleeding
  • Incarcerated hernia
  • Mesenteric thrombosis (bowel necrosis)
  • Generalized purulent peritonitis

For uncomplicated appendicitis, cholecystitis, pancreatitis — surgery within the next 24–72 hours after stabilization. Destructive pancreatitis is initially managed conservatively in the ICU.

Mistakes that must not be made

  • Prescribing analgesics before surgical examination — "masks" the clinical picture (although modern protocols allow pain relief, the classical principle is important for the exam)
  • Ectopic pregnancy not ruled out — hCG is mandatory in all women of childbearing age with abdominal pain
  • Abdominal form of myocardial infarction — ECG for epigastric pain!
  • Mesenchymal ischemia — "pain out of proportion to findings" (severe pain with a soft abdomen in the early stages)

Frequently asked questions

How to distinguish surgical acute abdomen from non-surgical?

Key signs of surgical pathology: peritoneal signs (Shchetkin-Blumberg sign), progressive pain, impaired passage (vomiting, delayed stool and gas), free gas or fluid on X-ray/ultrasound, leukocytosis with a shift. Non-surgical causes (diabetic abdominal crisis, porphyria, renal colic) usually do not present with muscle defense and peritoneal signs.

Why does pain start in the epigastrium in appendicitis?

This is due to dual innervation: initial visceral pain (via Th10 sympathetic fibers) is projected to the periumbilical/epigastric region. When the inflammation reaches the parietal peritoneum, the pain "migrates" to the right iliac region (somatic pain via Th11-L1). This phenomenon is Kocher-Volkovich sign.

Study surgery through interactive lessons on the platform. Related topics: peptic ulcer disease, pathophysiology of inflammation, tissue necrosis. Use clinical calculators to assess severity.

This material is educational in nature and does not replace a doctor's consultation. Verify treatment regimens and dosages with current clinical guidelines.

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